Welcome to the Proton MRS Validation Effort Resource Initiative (1HMRS-VERI)!
1HMRS-VERI (the Proton MRS Validation Effort Resource Initiative) represents a special endeavor from within the 2021/22 MRS Code and Data Sharing Committee and MRSHub to provide a centralized means to share spectral datasets that can be used to quantitatively validate proton magnetic resonance spectral processing and quantification tools. The tools to be validated include not only those that have already persisted in the literature absent centralized validation efforts but also as-yet agreed upon novel software solutions, open-source and otherwise, that might underlie future consensus recommendations regarding precise and accurate spectral processing and quantification pipelines.
• 1H-MRS acquisitions from phantoms, commercial or in-house, of premeasured metabolite concentrations;
• Well defined “gold standard” simulations of metabolite 1H-MR spectra including simulated and/or measured in vivo-like contributions to the data (e.g., macromolecules, extravoxel lipids, residual water, lineshape distortions from static field inhomogeneity, and other features that might be exhibited by in vivo spectral datasets);
• In vivo 1H-MR spectral acquisitions from human or other tissues within the context of experiments that also contain supporting measurements of metabolite concentration from non-1HMRS experiments, including X-nuclear MRS and/or non-MRS assays;
Not sure if your data set belongs here? Want to contribute something more? Email Kelley Swanberg at firstname.lastname@example.org.
Integrated into the data collections featured on MRSHub, browse or contribute datasets used for validating 1H-MRS processing and quantification pipelines.
Connect with others in the MRS community about the latest developments in proton MRS data processing and quantification pipeline validation.